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ネコカリシウイルス(FCV)の分子多様性に関する研究
https://az.repo.nii.ac.jp/records/4684
https://az.repo.nii.ac.jp/records/46847d366b4d-cec3-4ab2-a475-0d0025f5da22
名前 / ファイル | ライセンス | アクション |
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bull_jau_vol9-10-215.pdf (626.9 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2004-01-01 | |||||
タイトル | ||||||
タイトル | ネコカリシウイルス(FCV)の分子多様性に関する研究 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Study on the molecule diversity of Feline Calicivirus (FCV) | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ページ属性 | ||||||
内容記述タイプ | Other | |||||
内容記述 | P(論文) | |||||
記事種別 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 特集 | |||||
Type | ||||||
内容記述タイプ | Other | |||||
内容記述 | FEATURE ARTICLES | |||||
著者 |
原, 元宣
× 原, 元宣× 木内, 明男× 福山, 正文× Hara, Motomobu× Kiuchi, Akio× Fukuyama, Masafumi |
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著者ID | ||||||
000039 | ||||||
著者ID | ||||||
000044 | ||||||
著者ID | ||||||
000119 | ||||||
Author ID | ||||||
000039 | ||||||
Author ID | ||||||
000044 | ||||||
Author ID | ||||||
000119 | ||||||
所属機関 | ||||||
麻布大学 獣医学部 微生物学第2研究室 | ||||||
所属機関 | ||||||
麻布大学 獣医学部 微生物学第1研究室 | ||||||
所属機関 | ||||||
麻布大学 環境保健学部 微生物学研究室 | ||||||
Institution or Company | ||||||
Department of Microbiology 2, School of Veterinary Medicine, Azabu University | ||||||
Institution or Company | ||||||
Department of Microbiology 1, School of Veterinary Medicine, Azabu University | ||||||
Institution or Company | ||||||
Department of Microbiology, School of Environmental Health, Azabu University | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 一般的に雄は仔猫に興味を示すことはなく,仔猫の世話をするのは専ら雌猫であるが,今回は,雄成猫が感染源となり,仔猫へ感染するという結果となった。 | |||||
Abstract | ||||||
内容記述タイプ | Other | |||||
内容記述 | A multicat household experienced an epidemic of feline calicivirus (FCV) infection. We analyzed molecular evolution of isolated FCVs by a phylogenic tree reconstructed around the genotype of FCV that was isolated from the cat of infectious origin. FCV was isolated from eight of 34 cats: two 1-year-old, male littermates that became latent carriers (Ao198-1 and Ao199-1); two 3-month-old littermates (Ao222-1 and Ao224-1); three 4-month-old littermates (Ao210-1, Ao212-1 and Ao213-1) and a 5-month old (Ao210-1). All the isolates belonged to the genogroup II, and their nucleotide sequences showed >94% homology. They were subdivided into six distinct clusters by phylogenetic analysis, and Ao198-1, the source of infection, was most closely related to Ao199-1, then Ao212-1, Ao210-1, Ao214-1, Ao213-1, Ao222-1and Ao224-1 in this order. The similar result was obtained by phylogenic analysis of amino acid sequences. Sequence alignments of the isolates showed that the nonsynonymous substitution/total number of nucleotides ratio was <40% in the regions A, B, D and F, and >60% in the regions C and E. The nucleotide substitution/total number of nucleotides ratio was 33%, 12% and 15.6% at the region C and two hypervariable regions (5'and 3'HVRs) of the region E, respectively, and less than 10% at the other regions. For amino acids, the ratio was 50%, 24%, 10.3% and 25% at 5' and 3'HVRs of the regions C and E, respectively, especially high at the 5'HVR of the region C. The other regions were less than 10%. Our result suggested that the virus, while its transmission to the newborn cats, underwent frequent mutation especially at the regions C and E, suggesting these regions were most often involved in evolution of the FCV genome. | |||||
書誌情報 |
麻布大学雑誌 en : Journal of Azabu University 巻 9/10, p. 215-220, 発行日 2005-03-31 |
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出版者 | ||||||
出版者 | 麻布大学 | |||||
Publisher | ||||||
出版者 | Azabu University | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1346-5880 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11561468 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
text version | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
format | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf |