| Item type |
紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2004-01-01 |
| タイトル |
|
|
タイトル |
ネコカリシウイルス(FCV)の分子多様性に関する研究 |
| タイトル |
|
|
タイトル |
Study on the molecule diversity of Feline Calicivirus (FCV) |
|
言語 |
en |
| 言語 |
|
|
言語 |
jpn |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| ページ属性 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
P(論文) |
| 記事種別 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
特集 |
| Type |
|
|
内容記述タイプ |
Other |
|
内容記述 |
FEATURE ARTICLES |
| 著者 |
原, 元宣
木内, 明男
福山, 正文
Hara, Motomobu
Kiuchi, Akio
Fukuyama, Masafumi
|
| 著者ID |
|
|
|
000039 |
| 著者ID |
|
|
|
000044 |
| 著者ID |
|
|
|
000119 |
| Author ID |
|
|
|
000039 |
| Author ID |
|
|
|
000044 |
| Author ID |
|
|
|
000119 |
| 所属機関 |
|
|
|
麻布大学 獣医学部 微生物学第2研究室 |
| 所属機関 |
|
|
|
麻布大学 獣医学部 微生物学第1研究室 |
| 所属機関 |
|
|
|
麻布大学 環境保健学部 微生物学研究室 |
| Institution or Company |
|
|
|
Department of Microbiology 2, School of Veterinary Medicine, Azabu University |
| Institution or Company |
|
|
|
Department of Microbiology 1, School of Veterinary Medicine, Azabu University |
| Institution or Company |
|
|
|
Department of Microbiology, School of Environmental Health, Azabu University |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
一般的に雄は仔猫に興味を示すことはなく,仔猫の世話をするのは専ら雌猫であるが,今回は,雄成猫が感染源となり,仔猫へ感染するという結果となった。 |
| Abstract |
|
|
内容記述タイプ |
Other |
|
内容記述 |
A multicat household experienced an epidemic of feline calicivirus (FCV) infection. We analyzed molecular evolution of isolated FCVs by a phylogenic tree reconstructed around the genotype of FCV that was isolated from the cat of infectious origin. FCV was isolated from eight of 34 cats: two 1-year-old, male littermates that became latent carriers (Ao198-1 and Ao199-1); two 3-month-old littermates (Ao222-1 and Ao224-1); three 4-month-old littermates (Ao210-1, Ao212-1 and Ao213-1) and a 5-month old (Ao210-1). All the isolates belonged to the genogroup II, and their nucleotide sequences showed >94% homology. They were subdivided into six distinct clusters by phylogenetic analysis, and Ao198-1, the source of infection, was most closely related to Ao199-1, then Ao212-1, Ao210-1, Ao214-1, Ao213-1, Ao222-1and Ao224-1 in this order. The similar result was obtained by phylogenic analysis of amino acid sequences. Sequence alignments of the isolates showed that the nonsynonymous substitution/total number of nucleotides ratio was <40% in the regions A, B, D and F, and >60% in the regions C and E. The nucleotide substitution/total number of nucleotides ratio was 33%, 12% and 15.6% at the region C and two hypervariable regions (5'and 3'HVRs) of the region E, respectively, and less than 10% at the other regions. For amino acids, the ratio was 50%, 24%, 10.3% and 25% at 5' and 3'HVRs of the regions C and E, respectively, especially high at the 5'HVR of the region C. The other regions were less than 10%. Our result suggested that the virus, while its transmission to the newborn cats, underwent frequent mutation especially at the regions C and E, suggesting these regions were most often involved in evolution of the FCV genome. |
| 書誌情報 |
麻布大学雑誌
en : Journal of Azabu University
巻 9/10,
p. 215-220,
発行日 2005-03-31
|
| 出版者 |
|
|
出版者 |
麻布大学 |
| Publisher |
|
|
出版者 |
Azabu University |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1346-5880 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11561468 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| text version |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| format |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
bull_jau_vol9-10-215.pdf (626.9 kB)
