| Item type |
紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2006-01-01 |
| タイトル |
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タイトル |
初乳抗体による腸管内での病原性大腸菌の定着阻止および毒素の中和 |
| タイトル |
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タイトル |
Inhibition of colonization and neutralization of verotoxin of enterohemorrhagic Escherichia coli 157 : H7 by bovine colostral antibodies in beagle dogs |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
departmental bulletin paper |
| ページ属性 |
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内容記述タイプ |
Other |
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内容記述 |
P(論文) |
| 記事種別 |
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内容記述タイプ |
Other |
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内容記述 |
特集 |
| Type |
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内容記述タイプ |
Other |
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内容記述 |
FEATURE ARTICLES |
| 著者 |
山本, 静雄
栗林, 尚志
福山, 正文
古畑, 勝則
Yamamoto, Shizuo
Kuribayashi, Takashi
Fukuyama, Masafumi
Furuhata, Katsunori
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| 著者ID |
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000117 |
| 著者ID |
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000345 |
| 著者ID |
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000119 |
| 著者ID |
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000279 |
| Author ID |
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000117 |
| Author ID |
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000345 |
| Author ID |
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000119 |
| Author ID |
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000279 |
| 所属機関 |
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麻布大学大学院環境保健学研究科免疫学分野 |
| 所属機関 |
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麻布大学大学院環境保健学研究科免疫学分野 |
| 所属機関 |
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麻布大学大学院環境保健学研究科微生物学分野 |
| 所属機関 |
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麻布大学大学院環境保健学研究科微生物学分野 |
| Institution or Company |
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Laboratory of Immunology, Graduate School of Azabu University |
| Institution or Company |
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Laboratory of Immunology, Graduate School of Azabu University |
| Institution or Company |
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Laboratory of Microbiology, Graduate School of Azabu University |
| Institution or Company |
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Laboratory of Microbiology, Graduate School of Azabu University |
| Abstract |
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内容記述タイプ |
Other |
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内容記述 |
The aims of this study were to evaluate the imhibition of colonization and the neutralization of verotoxin (VT) of enterohemorrhagic Escherichia coli O157 colostral antibodies in beagle dogs. Cows were immunized with bacterial cells (O157) purified VT2 14 times at 7-day intervals. Colostral antibodies were obtained from immunized cows after delivery. The titer of bovine colostral antibody to VT was high. But, the titer of antibody to flagellum was very low. IgA antibody titer to VT was higher than IgG or IgM antibody titer. Beagle dogs inoculated with O157 producing VT2 were administered colostral antibody, serum antibody or saline. Furthremore, colostral antibody and colostrum whey obtained from non-immunized cow were administrated. The amount of VT2 in feces was reduced immediately by administration of colostral antibody than plasma antibody, saline or colostrum whey. The residual time in small intestine of bovine colostral antibody and plasma antibody obtained from rabitts immunized VT2 was compared. The residual time of bovine colostral antibody was longer than rabbit serum antibody. This result suggested that bovine colostral antibody resisted to protease in digestive organ. |
| 書誌情報 |
麻布大学雑誌
en : Journal of Azabu University
巻 13/14,
p. 226-228,
発行日 2007-03-31
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| 出版者 |
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出版者 |
麻布大学 |
| Publisher |
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出版者 |
Azabu University |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1346-5880 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11561468 |
| 著者版フラグ |
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| text version |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| format |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
bull_jau_vol13-14-226.pdf (217.4 kB)
