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形質転換植物を用いたダイオキシン類による汚染環境のバイオモニタリングに関する基礎研究
https://az.repo.nii.ac.jp/records/4690
https://az.repo.nii.ac.jp/records/4690b42b9dcc-4a4f-4502-8f9f-ee117621d5f8
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
bull_jau_vol9-10-239.pdf (111.7 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2004-01-01 | |||||||||||
| タイトル | ||||||||||||
| タイトル | 形質転換植物を用いたダイオキシン類による汚染環境のバイオモニタリングに関する基礎研究 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Studies on biomonitoring and phytoremediation of dioxins in the polluted environment using transgenic plants.(Research Group 3) | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | jpn | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| ページ属性 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | P(論文) | |||||||||||
| 記事種別 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | 特集 | |||||||||||
| Type | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | FEATURE ARTICLES | |||||||||||
| 著者 |
其木, 茂則
× 其木, 茂則
× Sonoki, Shigenori
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| 著者ID | ||||||||||||
| 000120 | ||||||||||||
| Author ID | ||||||||||||
| 000120 | ||||||||||||
| 所属機関 | ||||||||||||
| 環境保健学部 | ||||||||||||
| Institution or Company | ||||||||||||
| School of Environmental Health | ||||||||||||
| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | リアルタイムPCR法を用いて,化学物質代謝のphase 1,phase 2に関与するチトクロームP450,グルタチオンS-トランスフェラーゼ,パーオキシダーゼ遺伝子の発現がPCB126暴露時間に依存して促進されることが見いだされた。 | |||||||||||
| Abstract | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | It has been of great concern that halogenated aromatic hydrocarbons cause the disruption in the endocrine system of animals. Among them huge amount of polychlorinated biphenyls (PCBs), because of their non-flammability, chemical stability, high boiling point and electrical insulating properties, have been used for industrial and commercial applications from 1960's. Among the possible 209 PCB congeners, the environmental toxicity of coplanar PCBs (Co-PCBs) is becoming more severe especially in Japan. In this study, the gene(s) that respond to the chemical stress of Co-PCBs in the genome of plant, Arabidopsis thaliana, was (were) searched using real time PCR method. This study, which intends to use the plant gene(s) as a biomarker for monitoring the environmental levels of Co-PCBs, is expected to lead to the development of a new strategy in the risk assessment of Co-PCB contamination. As a result, four isoforms in cytochrome P450 monooxygenases (CYP) that were involved in the first phase of xenobiotic transformation and five isoforms in glutathione S-transferases (GST) that were involved in the second phase were found to be up-regulated by the exposure to PCB 126 for 2h, but on the other five isoforms in peroxidases seemed to be up-regulated late compared to CYP and GST by 48 h-exposure to PCB 126. These genes are expected to be the candidate for a biomarker in the environmental monitoring of Co-PCB. | |||||||||||
| 書誌情報 |
麻布大学雑誌 en : Journal of Azabu University 巻 9/10, p. 239-240, 発行日 2005-03-31 |
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| レポート・演題番号 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | 麻布大学ハイテク・リサーチ・センター研究プロジェクト 研究サブ・グループ3 | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | 麻布大学 | |||||||||||
| Publisher | ||||||||||||
| 出版者 | Azabu University | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 1346-5880 | |||||||||||
| 書誌レコードID | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA11561468 | |||||||||||
| 著者版フラグ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| text version | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| format | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | application/pdf | |||||||||||
