| Item type |
紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2000-01-01 |
| タイトル |
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タイトル |
Helicobacter pylori感染スナネズミにおける魚粉の胃炎促進作用 |
| タイトル |
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タイトル |
Fish Meal Significantly Enhanced Helicobacter pylori-induced Gastritis in Mongolian Gerbils |
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言語 |
en |
| 言語 |
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言語 |
jpn |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
|
主題 |
Helicobacter pylori |
| キーワード |
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Mongolian gerbil |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
gastritis |
| キーワード |
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
fish meal |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
departmental bulletin paper |
| ページ属性 |
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内容記述タイプ |
Other |
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内容記述 |
P(論文) |
| 記事種別 |
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内容記述タイプ |
Other |
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内容記述 |
原著論文 |
| Type |
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内容記述タイプ |
Other |
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内容記述 |
ORIGINAL ARTICLE |
| 著者 |
寺本, 由里香
谷川, 徹也
飯室, 正樹
若林, 敬二
福山, 正文
TERAMOTO, Yurika
TANIGAWA, Tetsuya
IIMURO, Masaki
WAKABAYASHI, Keiji
FUKUYAMA, Masafumi
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- |
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- |
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- |
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- |
| 著者ID |
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000119 |
| Author ID |
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- |
| Author ID |
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- |
| Author ID |
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- |
| Author ID |
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- |
| Author ID |
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000119 |
| 所属機関 |
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麻布大学大学院環境保健学研究科 |
| 所属機関 |
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国立がんセンター研究所がん予防研究部 |
| 所属機関 |
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国立がんセンター研究所がん予防研究部 |
| 所属機関 |
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国立がんセンター研究所がん予防研究部 |
| 所属機関 |
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麻布大学大学院環境保健学研究科 |
| Institution or Company |
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Graduate School of Environmental Health, Azabu University |
| Institution or Company |
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Cancer Prevention Division, National Cancer Center Research Institute |
| Institution or Company |
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Cancer Prevention Division, National Cancer Center Research Institute |
| Institution or Company |
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Cancer Prevention Division, National Cancer Center Research Institute |
| Institution or Company |
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Graduate School of Environmental Health, Azabu University |
| Abstract |
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内容記述タイプ |
Other |
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内容記述 |
Epidemiological and laboratory animal studies have suggested a positive association between Helicobacter pylori infection and gastric carcinogenesis. In Japan, gastric cancer is the most common and leading cause of cancer death. This study was designed to investigate the effects of fish meal on H. pyloriinduced gastritis in Mongolian gerbils in order to find dietary factors associated with gastric carcinogenesis. Male 7 week-old Mongolian gerbils were inoculated with H. pylori (ATCC43504) 0.5 ml (0.5×10^9CFUs) by gavage and a dietary regimen maintained as follows for 4 weeks : 0% fish meal (casein instead of fish meal in conventional diet); 10% fish meal (conventional diet); 20% fish meal (conventional diet plus 10% fish meal). All animals were sacrificed at 4 weeks after inoculation with H. pylori. In all gerbils inoculated with H. pylori, about 10^5 viable bacteria were counted, without any significant intergroup differences. In macroscopic findings, gastric edema and hemorrhage were observed in 10 and 5, 95 and 55, and 95 and 85% of animals in the 0, 10, and 20% fish meal diet groups, respectively. Histopathological examinations indicated that a fish meal diet significantly increased activity and inflammation indices of the stomach in a dose-dependent manner. These results suggest that some dietary factors in a fish meal diet enhance H. pylori-induced gastritis and may be dietary factors which enhance gastric carcinogenesis. |
| 書誌情報 |
麻布大学雑誌
en : Journal of Azabu University
巻 1/2,
p. 9-14,
発行日 2001-03-31
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| 出版者 |
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出版者 |
麻布大学 |
| Publisher |
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出版者 |
Azabu University |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1346-5880 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA11561468 |
| 著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| text version |
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| format |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
bull_jau_vol1-2-009.pdf (584.6 kB)
