{"_buckets": {"deposit": "fbea9416-471d-45a0-92e5-db1ddef5b448"}, "_deposit": {"created_by": 4, "id": "3735", "owners": [4], "pid": {"revision_id": 0, "type": "depid", "value": "3735"}, "status": "published"}, "_oai": {"id": "oai:az.repo.nii.ac.jp:00003735", "sets": ["211", "288", "453"]}, "author_link": ["17487", "17486", "17483", "17485", "17488", "17484"], "item_12_biblio_info_16": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013-01-31", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "20", "bibliographicPageStart": "13", "bibliographicVolumeNumber": "24", "bibliographic_titles": [{"bibliographic_title": "麻布大学雑誌"}, {"bibliographic_title": "Journal of Azabu University", "bibliographic_titleLang": "en"}]}]}, "item_12_description_13": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "合成エストロジェンであるジエチルスチルベステロール（DES）を1.5 あるいは0.5 μ g/kg/day（DES 1.5 群あるいはDES 0.5群）の用量で妊娠SD ラットに妊娠7 日目～ 21 日目の期間，連日皮下投与し，産子の子宮の発達に対してどのような影響を及ぼすかについて検討した。胎齢20 日のDES1.5群において，子宮角の長さが増加し，生後3，6 および15 週の長さは短くなった。生後3 および6 週齢のDES1.5 群の子宮角の太さが増加した。さらに生後1 週の子宮内膜上皮細胞の細胞分裂指数も有意に増加した。以上の結果から，胎生期に投与された低濃度のDES は雌産子の子宮の発達に対して促進的な作用を有するが，その作用は恒久的ではないことが示唆された。", "subitem_description_type": "Abstract"}]}, "item_12_description_14": {"attribute_name": "Abstract", "attribute_value_mlt": [{"subitem_description": "Diethylstilbestrol (DES), synthetic estrogen, was administered subcutaneously at 0.5 (DES 0.5group) or 1.5 μ g/kg/day (DES 1.5 group) to pregnant Sprague-Dawley (SD) rats daily form days 7 to 21 of gestation to investigate its effects on the development of uteri in female offspring. The lengths of uterine horn in the DES 1.5 group were significantly longer at 20 days of gestation and were significantly shorter at 3, 6 and 15 weeks after birth. The diameters of uterine horns in the DES 1.5 group were significantly larger at 3 and 6 weeks after birth. Furthermore the cell division index of the uterine epithelium in the DES 1.5 group was significantly increased. These observations indicate that prenatal exposure to a low dose of DES a promotes the development of uteri in female SD offspring, but this stimulus effect is not permanent.", "subitem_description_type": "Other"}]}, "item_12_description_2": {"attribute_name": "ページ属性", "attribute_value_mlt": [{"subitem_description": "P(論文)", "subitem_description_type": "Other"}]}, "item_12_description_24": {"attribute_name": "NII論文ID(NAID)", "attribute_value_mlt": [{"subitem_description": "40019736709", "subitem_description_type": "isIdenticalTo"}]}, "item_12_description_3": {"attribute_name": "記事種別", "attribute_value_mlt": [{"subitem_description": "原著論文", "subitem_description_type": "Other"}]}, "item_12_description_34": {"attribute_name": "format", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_12_description_4": {"attribute_name": "Type", "attribute_value_mlt": [{"subitem_description": "ORIGINAL ARTICLE", "subitem_description_type": "Other"}]}, "item_12_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.14944/00003714", "subitem_identifier_reg_type": "JaLC"}]}, "item_12_publisher_19": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "麻布大学"}]}, "item_12_publisher_20": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_publisher": "Azabu University"}]}, "item_12_source_id_21": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1346-5880", "subitem_source_identifier_type": "ISSN"}]}, "item_12_source_id_23": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11561468", "subitem_source_identifier_type": "NCID"}]}, "item_12_text_10": {"attribute_name": "Author ID", "attribute_value_mlt": [{"subitem_text_value": "-"}, {"subitem_text_value": "000040"}, {"subitem_text_value": "000047"}]}, "item_12_text_11": {"attribute_name": "所属機関", "attribute_value_mlt": [{"subitem_text_value": "西川動物病院, 麻布大学獣医学部"}, {"subitem_text_value": "麻布大学獣医学部"}, {"subitem_text_value": "麻布大学獣医学部"}]}, "item_12_text_12": {"attribute_name": "Institution or Company", "attribute_value_mlt": [{"subitem_text_value": "Nishikawa Animal Hospital, Azabu University,School of Veterinary Medicine"}, {"subitem_text_value": "Azabu University,School of Veterinary Medicine"}, {"subitem_text_value": "Azabu University,School of Veterinary Medicine"}]}, "item_12_text_9": {"attribute_name": "著者ID", "attribute_value_mlt": [{"subitem_text_value": "-"}, {"subitem_text_value": "000040"}, {"subitem_text_value": "000047"}]}, "item_12_version_type_29": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_12_version_type_30": {"attribute_name": "text version", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "西川, 修"}], "nameIdentifiers": [{"nameIdentifier": "17483", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "政岡, 俊夫"}], "nameIdentifiers": [{"nameIdentifier": "17484", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "有嶋, 和義"}], "nameIdentifiers": [{"nameIdentifier": "17485", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nishikawa, Osamu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "17486", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Masaoka, Toshio", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "17487", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Arishima, Kazuyoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "17488", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2014-03-27"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "bull_jau_vol24-013.pdf", "filesize": [{"value": "2.6 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2600000.0, "url": {"label": "bull_jau_vol24-013", "url": "https://az.repo.nii.ac.jp/record/3735/files/bull_jau_vol24-013.pdf"}, "version_id": "7584b8e7-a866-42b1-83ca-76d8f31499e9"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Diethylstilbetrol", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Uterus", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Prenatal administration", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Rat", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "低用量Diethylstilbestrol の妊娠ラットへの投与が雌産子子宮の発達へ及ぼす影響", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "低用量Diethylstilbestrol の妊娠ラットへの投与が雌産子子宮の発達へ及ぼす影響"}, {"subitem_title": "Effects of maternal exposure to a low dose of diethylstilbestrol on the development of the uterus in female rat offspring.", "subitem_title_language": "en"}]}, "item_type_id": "12", "owner": "4", "path": ["211", "288", "453"], "permalink_uri": "https://doi.org/10.14944/00003714", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-03-20"}, "publish_date": "2014-03-20", "publish_status": "0", "recid": "3735", "relation": {}, "relation_version_is_last": true, "title": ["低用量Diethylstilbestrol の妊娠ラットへの投与が雌産子子宮の発達へ及ぼす影響"], "weko_shared_id": 4}