| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2026-03-10 |
| タイトル |
|
|
タイトル |
Detection and genetic analysis of bovine rhinitis B virus in Japan |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Ishida, Hiroho
Nakamura, Mikari
Murakami, Hironobu
Kazama, Kei
Oba, Mami
Takemae, Hitoshi
Mizutani, Tetsuya
Ouchi, Yoshinao
Kawakami, Junko
Tsuzuku, Satoko
Nagai, Makoto
|
| Abstract |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Bovine rhinitis B virus (BRBV) (genus Aphthovirus, family Picornaviridae) is a significant etiological agent of the bovine respiratory disease complex. Despite global reports on BRBV, genomic data for Japanese strains are not available. In this study, we aimed to obtain genomic information on BRBV in Japan and analyze its genetic characteristics. In nasal swabs from 66 cattle, BRBV was detected in 6 out of 10 symptomatic and 4 out of 56 asymptomatic cattle. Using metagenomic sequencing and Sanger sequencing, the nearly complete genome sequences of two Japanese BRBV strains, IBA/2211/2 and LAV/238002, from symptomatic and asymptomatic cattle, respectively, were determined. These viruses shared significant genetic similarity with known BRBV strains and exhibited unique mutations and recombination events, indicating dynamic evolution, influenced by regional environmental and biological factors. Notably, the leader gene was only approximately 80% and 90% identical in its nucleotide and amino acid sequence, respectively, to all of the BRBV strains with sequences in the GenBank database, indicating significant genetic divergence in the Japanese BRBV leader gene. These findings provide insights into the genetic makeup of Japanese BRBV strains, enriching our understanding of their genetic diversity and evolutionary mechanisms. |
|
言語 |
en |
| 書誌情報 |
Archives of Virology
巻 169,
号 6,
p. 125-125,
発行日 2024-05-16
|
| 出版者 |
|
|
出版者 |
Springer Nature |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1007/s00705-024-06046-y |
| 著者版フラグ |
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|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 査読 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
査読あり |
Ishida et al. Detection and genetic analysis of bovine rhinitis B virus in Japan.pdf (1.2 MB)
