Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2025-03-14 |
タイトル |
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タイトル |
Verification of a simplified disk diffusion method for antimicrobial susceptibility testing of bovine mastitis isolates |
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言語 |
en |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
著者 |
Kurumisawa, Tomomi
Kawai, Kazuhiro
Shinozuka, Yasunori
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Abstract |
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内容記述タイプ |
Abstract |
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内容記述 |
Bovine mastitis is mainly treated with antimicrobials. Determination of antimicrobial treatments based on the results of an antimicrobial susceptibility test is important to reduce the risk of emergence of antimicrobial resistance and to provide effective treatment. In Japan, not only the standardized agar disk diffusion method (standardized-ADD) based on Clinical and Laboratory Standards Institute guidelines, but also the agar disk diffusion method further simplified (simplified-ADD) are widely used as antimicrobial susceptibility tests for bovine mastitis isolates in the clinical laboratory. However, whether the simplified-ADD is a useful alternative to the standardized-ADD has not yet been sufficiently verified. Therefore, to verify the usefulness of the simplified-ADD, we compared the results of the standardized-ADD and the simplified-ADD using clinical isolates of bovine mastitis. Following testing of 83 isolates from 11 bacterial species, the correlation coefficient of the disk zone diameters in both methods was 0.92, indicating that the simplified-ADD is effective as an alternative method to the standardized-ADD. However, because the disk zone diameter tended to be smaller in the simplified-ADD than in the standardized-ADD, sufficient attention should be paid to this point when determining the treatment for clinical cases of mastitis from the results of the simplified-ADD. The fact that a difference in the results between the two methods was present means that the results cannot be interpreted based on the same criteria. Therefore, determination of the criteria appropriate for the simplified-ADD is needed. |
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言語 |
en |
bibliographic_information |
Japanese Journal of Veterinary Research
巻 69,
号 2,
p. 135-143,
発行日 2021-05
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出版者 |
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出版者 |
Faculty of Veterinary Medicine, Hokkaido University |
item_10002_source_id_9 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0047-1917 |
item_10002_relation_14 |
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識別子タイプ |
DOI |
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関連識別子 |
10.14943/jjvr.69.2.135 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
item_1730428627434 |
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内容記述タイプ |
Other |
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内容記述 |
査読あり |