@article{oai:az.repo.nii.ac.jp:00005157,
 author = {川上, 泰 and 内田, 明彦 and 森田, 重光 and Kawakami, Yasushi and Uchida, Akihiko and Morita, Sigemitsu},
 journal = {麻布大学雑誌, Journal of Azabu University},
 month = {Mar},
 note = {ネコ由来のマンソン裂頭条虫成虫から,4糖からなる糖脂質を単離・精製し,MALDI-TOF/MSにより分析した結果,糖組成はヘキソースが4つという結果であった。この結果は,イヌ由来の成虫を用いた分析結果と一致し,成虫特異的であった。すなわち幼虫と成虫に存在するスピロメトシドがフコースを含むのに対し,成虫でのみフコースを含まないヘキソース4糖からなる成分が発現することになる。このことから,幼虫から成虫に発育することにより,存在する糖脂質が一部変化していることがわかった。しかしながら宿主の違いによる糖脂質の変異は認められなかった。, Glycosphingolipids (GSLs) can be expected to be involved in the mediation of host-parasite interactions, as are functioning in bacterial and viral infection. In this context, we have been studying GSLs of cestodes to elucidate underlying biochemical mechanisms of parasitism. In this study, GSLs were purified from larvae and adults of the tapeworms, Spirometra erinaceieuropaei, and their chemical structures were determined. Total lipid fractions prepared from chloroform/methanol extracts of whole tissues were fractionated successively on ion-exchange chromatography, silicic acid column chromatography, and preparative TLC. The purified GSLs characterized by TLC-immunostaining, permethylation analysis, MALDI-TOF/MS. The GSLs Gall-4Glcl-3(Gall-6)Gall-Cer was found in adult worms but not in larvae. These findings suggested that GSL compositions were significantly different between adults and larvae., P(論文), 特集, application/pdf, FEATURE ARTICLES},
 pages = {257--260},
 title = {条虫類に存在する糖脂質の化学構造解析},
 volume = {13/14},
 year = {2007},
 yomi = {カワカミ, ヤスシ and ウチダ, アキヒコ and モリタ, シゲミツ}
}