{"created":"2023-06-19T07:19:05.231087+00:00","id":4871,"links":{},"metadata":{"_buckets":{"deposit":"75c485f8-be9c-4791-a609-7447fcb105ca"},"_deposit":{"created_by":4,"id":"4871","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"4871"},"status":"published"},"_oai":{"id":"oai:az.repo.nii.ac.jp:00004871","sets":["31:181:508"]},"author_link":["21265","21264","21262","21263"],"item_12_biblio_info_16":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"241","bibliographicPageStart":"239","bibliographicVolumeNumber":"11/12","bibliographic_titles":[{"bibliographic_title":"麻布大学雑誌"},{"bibliographic_title":"Journal of Azabu University","bibliographic_titleLang":"en"}]}]},"item_12_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"DNAマイクロアレイを用いて,コプラナーPCBによって影響を受けるマスト細胞の遺伝資群の網羅的な解析を行った。コプラナーPCBの一つであるPCB126によって発現が上昇した遺伝子は6遺伝子あり,主な遺伝子はライソザイム関連遺伝子であり,免疫関連遺伝子は認められなかった。一方,PCB126によって発現が減少した遺伝子はほとんどなく,免疫関連遺伝子は認められなかった。以上の結果より,コプラナーPCBによるマスト細胞の免疫関連遺伝子への直接的な影響は認められず,以前の結果から示唆されるようにPCBの免疫系への影響はクロストークなどを含めた間接的な作用による可能性が示唆された。","subitem_description_type":"Abstract"}]},"item_12_description_14":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Using DNA micro array, mast cell gene profiles which is caused by the influenced of coplanar PCB was exhaustively examined. Up-regulated mRNAs in mast cell treated with PCB126, one of coplanar PCB congeners, were six genes. Almost all were lysozyme-associating genes, but not immune-associating. On the other hand, down-regulated genes in the treated mast cell were a few and immune associating gene was none. Our findings suggest that the influence of coplanar PCB in the immune-associating genes of mast cell is indirectly effect, such as cross-talking et al.","subitem_description_type":"Other"}]},"item_12_description_18":{"attribute_name":"レポート・演題番号","attribute_value_mlt":[{"subitem_description":"麻布大学ハイテク・リサーチ・センター研究プロジェクト 研究サブ・グループ4","subitem_description_type":"Other"}]},"item_12_description_2":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_12_description_3":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_description":"特集","subitem_description_type":"Other"}]},"item_12_description_34":{"attribute_name":"format","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_12_description_4":{"attribute_name":"Type","attribute_value_mlt":[{"subitem_description":"FEATURE ARTICLES","subitem_description_type":"Other"}]},"item_12_publisher_19":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"麻布大学"}]},"item_12_publisher_20":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Azabu University"}]},"item_12_source_id_21":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-5880","subitem_source_identifier_type":"ISSN"}]},"item_12_source_id_23":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11561468","subitem_source_identifier_type":"NCID"}]},"item_12_text_11":{"attribute_name":"所属機関","attribute_value_mlt":[{"subitem_text_value":"麻布大学獣医学部"},{"subitem_text_value":"麻布大学獣医学部"}]},"item_12_text_12":{"attribute_name":"Institution or Company","attribute_value_mlt":[{"subitem_text_value":"School of Veterinary Medicine, Azabu University"},{"subitem_text_value":"School of Veterinary Medicine, Azabu University"}]},"item_12_version_type_29":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_12_version_type_30":{"attribute_name":"text version","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"池田, 輝雄"},{"creatorName":"イケダ, テルオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"舟場, 正幸"},{"creatorName":"フナバ, マサユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikeda, Teruo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Funaba, Masayuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2005-01-01"}],"displaytype":"detail","filename":"bull_jau_vol11-12-239.pdf","filesize":[{"value":"174.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"bull_jau_vol11-12-239.pdf","url":"https://az.repo.nii.ac.jp/record/4871/files/bull_jau_vol11-12-239.pdf"},"version_id":"a9720e8f-1ec1-4974-a851-4e5fc8361f0d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"マスト細胞活性化機構の解析を中心としたアレルギー疾患に及ぼすコプラナーPCBsの影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"マスト細胞活性化機構の解析を中心としたアレルギー疾患に及ぼすコプラナーPCBsの影響"},{"subitem_title":"The effects of Co-PCB in allergic disorder : Analyses of mast cell functions in response to Co-PCB","subitem_title_language":"en"}]},"item_type_id":"12","owner":"4","path":["508"],"pubdate":{"attribute_name":"公開日","attribute_value":"2005-01-01"},"publish_date":"2005-01-01","publish_status":"0","recid":"4871","relation_version_is_last":true,"title":["マスト細胞活性化機構の解析を中心としたアレルギー疾患に及ぼすコプラナーPCBsの影響"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-06-19T08:00:13.930916+00:00"}