{"created":"2023-06-19T07:19:00.391052+00:00","id":4669,"links":{},"metadata":{"_buckets":{"deposit":"dd5e6263-9b21-4ac7-b0bf-72a067daa1ee"},"_deposit":{"created_by":4,"id":"4669","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"4669"},"status":"published"},"_oai":{"id":"oai:az.repo.nii.ac.jp:00004669","sets":["17:234:238","17:253:312","17:257:355","31:181:490"]},"author_link":["20292","20289","20291","20294","20290","20293"],"item_12_biblio_info_16":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"157","bibliographicPageStart":"154","bibliographicVolumeNumber":"9/10","bibliographic_titles":[{"bibliographic_title":"麻布大学雑誌"},{"bibliographic_title":"Journal of Azabu University","bibliographic_titleLang":"en"}]}]},"item_12_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"レジオネラ属菌の除去を目的として,塩素系薬剤に替わる天然抗菌剤の検索を行うため,グレープフルーツ種子抽出物(GSE)について,L. pneumophilaに対する抗菌効果を検討したところ,以下の成績が得られた。1. L. pneumophilaに対するGSEの抗菌活性試験を行ったところ,供試した25菌株は17～25mmの範囲に明瞭な阻止円の形成を示し,平均値は20.8mmであった。2. L. pneumophilaに対するGSEのMIC値を測定したところ,範囲は97.7mg/lから390.6mg/lを示し,MIC_<90>は390.6mg/lであった。3. L. pneumophilaに対するGSEのMBC値を測定したところ,範囲は接触時間1分,10分,60分で12,500～50,000mg/l,1,563～6,250mg/l,781.3～3,125mg/lを示し,MBC_<90>は1分,10分,60分で,それぞれ50,000mg/l,6,250mg/l,3,125mg/lであった。4. 40℃に保温したpH7.0とpH9.0のリン酸緩衝液およびpH7.0のリン酸緩衝液に生薬を添加した溶液中にGSE100mg/lおよび1,000mg/lを含む溶液を用いて標準株と浴槽水由来株に対するGSEの殺菌効果を検討したところ,いずれの条件でも菌接種後1分以内で99.99%が殺菌された。以上のことから,GSEはL. pneumophilaに対して抗菌活性や殺菌効果を示すことが明らかとなった。","subitem_description_type":"Abstract"}]},"item_12_description_14":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"We investigated the antibacterial effect of commercial grapefruit seed extract (GSE, Liquid), which has recently been attracting attention as a food additive, on Legionella pneumophila. The sensitivity test was performed using the disc method. All 25 strains tested were sensitive to GSE, and formed clear inhibition zones in its presence. The minimum inhibitory concentration (MIC) values were measured by the agar dilution method. The MIC of GSE in the strains was in the range of 97.7 mg/l to 390.6 mg/l, and the MIC_<90> was 390.6 mg/l. The minimum bactericidal concentration (MBC) values for the test strains were also determined. MBC_<90> was 50,000, 6,250, and 3,125 mg/l when the exposure time was 1, 10, and 60 minutes, respectively. These bactericidal test results demonstrate that GSE has a bactericidal effect on L. pneumophila.","subitem_description_type":"Other"}]},"item_12_description_2":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_12_description_3":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_description":"特集","subitem_description_type":"Other"}]},"item_12_description_34":{"attribute_name":"format","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_12_description_4":{"attribute_name":"Type","attribute_value_mlt":[{"subitem_description":"FEATURE ARTICLES","subitem_description_type":"Other"}]},"item_12_publisher_19":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"麻布大学"}]},"item_12_publisher_20":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Azabu University"}]},"item_12_source_id_21":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-5880","subitem_source_identifier_type":"ISSN"}]},"item_12_source_id_23":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11561468","subitem_source_identifier_type":"NCID"}]},"item_12_text_10":{"attribute_name":"Author ID","attribute_value_mlt":[{"subitem_text_value":"000279 "},{"subitem_text_value":"000117"},{"subitem_text_value":"000114"}]},"item_12_text_11":{"attribute_name":"所属機関","attribute_value_mlt":[{"subitem_text_value":"麻布大学大学院環境保健学研究科"},{"subitem_text_value":"麻布大学大学院環境保健学研究科"},{"subitem_text_value":"麻布大学大学院環境保健学研究科"}]},"item_12_text_12":{"attribute_name":"Institution or Company","attribute_value_mlt":[{"subitem_text_value":"School of Environmental Health, Azabu University"},{"subitem_text_value":"School of Environmental Health, Azabu University"},{"subitem_text_value":"School of Environmental Health, Azabu University"}]},"item_12_text_9":{"attribute_name":"著者ID","attribute_value_mlt":[{"subitem_text_value":"000279 "},{"subitem_text_value":"000117"},{"subitem_text_value":"000114"}]},"item_12_version_type_29":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_12_version_type_30":{"attribute_name":"text version","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"古畑, 勝則"},{"creatorName":"フルハタ, カツノリ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山本, 静雄"},{"creatorName":"ヤマモト, シズオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, 潤"},{"creatorName":"スズキ, ジュン","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Furuhata, Katsunori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Shizuo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Jun","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2004-01-01"}],"displaytype":"detail","filename":"bull_jau_vol9-10-154.pdf","filesize":[{"value":"381.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"bull_jau_vol9-10-154.pdf","url":"https://az.repo.nii.ac.jp/record/4669/files/bull_jau_vol9-10-154.pdf"},"version_id":"40fee381-737d-4e80-8b44-efca222bfd41"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"レジオネラ属菌に対するグレープフルーツ種子抽出物の抗菌作用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"レジオネラ属菌に対するグレープフルーツ種子抽出物の抗菌作用"},{"subitem_title":"Antibacterial Activities of Grapefruit (Citrus paradisi) Seed Extract against Legionella pneumophila from Whirlpool Bath Waters","subitem_title_language":"en"}]},"item_type_id":"12","owner":"4","path":["238","312","355","490"],"pubdate":{"attribute_name":"公開日","attribute_value":"2004-01-01"},"publish_date":"2004-01-01","publish_status":"0","recid":"4669","relation_version_is_last":true,"title":["レジオネラ属菌に対するグレープフルーツ種子抽出物の抗菌作用"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2023-06-19T07:47:16.855239+00:00"}