@article{oai:az.repo.nii.ac.jp:00004613, author = {OHE, Kyoko and SAKAI, Sachi and SUNAGA, Fujiko and MURAKAMI, Masaru and KIUCHI, Akio and FUKUYAMA, Masafumi and FURUHATA, Katsunori and HARA, Motonobu and SOMA, Takehisa and ISHIKAWA, Yoshihisa and TANENO, Akira and OHE, Kyoko and SAKAI, Sachi and SUNAGA, Fujiko and MURAKAMI, Masaru and KIUCHI, Akio and FUKUYAMA, Masafumi and FURUHATA, Katsunori and HARA, Motonobu and SOMA, Takehisa and ISHIKAWA, Yoshihisa and TANENO, Akira}, journal = {麻布大学雑誌, Journal of Azabu University}, month = {Mar}, note = {A multicat household experienced an epidemic of feline calicivirus (FCV) infection. FCV was isolated from eight of 34 cats. We analyzed molecular evolution of isolated FCVs by a phylogenic tree. All the isolates belonged to the genogroup II, and their nucleotide sequences showed >94% identity. They were subdivided into six distinct clusters by phylogenetic analysis, and Ao198-1, the source of infection, was most closely related to Ao199-1, then Ao212-1, Ao210-1, Ao214-1, Ao213-1, Ao222-1 and Ao224-1 in this order. Sequence alignments of the isolates showed that the nonsynonymous substitution/total number of nucleotides ratio was <60% in the regions A, B, D conE and F, and >80% in the regions C and 5' and HVR of E. Our result suggested that the virus, while its transmission to the newborn cats, underwent frequent mutation especially at the regions C and E, suggesting these regions were most often involved in evolution of the FCV genome., P(論文), 原著論文, application/pdf, ORIGINAL ARTICLE}, pages = {1--9}, title = {Search of the Infections Source of feline calicivirus in a Multicat Household}, volume = {9/10}, year = {2005} }