{"created":"2023-06-19T07:18:36.334963+00:00","id":4111,"links":{},"metadata":{"_buckets":{"deposit":"6e33f033-7cbf-4dd6-a11c-87648e5e5fa6"},"_deposit":{"created_by":4,"id":"4111","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"4111"},"status":"published"},"_oai":{"id":"oai:az.repo.nii.ac.jp:00004111","sets":["31:181:480"]},"author_link":["18503","18499","18500","18496","18495","18502","18501","18497","18494","18498"],"item_12_biblio_info_16":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-03-20","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"16","bibliographicPageStart":"11","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"麻布大学雑誌"},{"bibliographic_title":"Journal of Azabu University","bibliographic_titleLang":"en"}]}]},"item_12_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"イヌのグルコース輸送体4（GluT4）の分子構造と組織発現を調べた。イヌGLUT4のcDNA配列全長1637bpであり，510のアミノ酸から構成され，ヒトとマウスより1アミノ酸大きいことが明らかとなった。このアミノ酸はヒトGluT4と95.2％，マウスGluT4と93.7％の相同性を示した。RT-PCRの結果，心臓・骨格筋・脂肪組織に発現がみられた。ウェスタンブロット解析により，GluT4タンパクは50kDaの質量をもつことが示された。イヌのインシュリン感受性グルコース輸送体4の構造が判明したことにより，イヌの糖尿病の病態生化学の理解に寄与するものと考えられる。","subitem_description_type":"Abstract"}]},"item_12_description_14":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Molecular structure and distribution of canine glucose transporter 4(GluT4)　were investigated. Canine GluT4 was consisted of 1637 nucleotides encoding 510 amino acids, which is one amino acid longer than human and mouse. Canine GluT4 exhibited 95.2% and 93.7% identity to human and mouse, respectively RT-PCR analysis indicated that its expression was confirmed in heart, skeletal muscle and lipocytes. Westernblot analysis showed the molecular weight of canine GluT4 was 50kDa. Molecular structure and distribution of insulin-sensitive GluT4 will contribute to a better understanding of the patho-physiology of canine diabetes.","subitem_description_type":"Other"}]},"item_12_description_2":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_12_description_3":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_description":"原著論文","subitem_description_type":"Other"}]},"item_12_description_34":{"attribute_name":"format","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_12_description_4":{"attribute_name":"Type","attribute_value_mlt":[{"subitem_description":"ORIGINAL ARTICLE","subitem_description_type":"Other"}]},"item_12_publisher_19":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"麻布大学"}]},"item_12_publisher_20":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Azabu University"}]},"item_12_source_id_21":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-5880","subitem_source_identifier_type":"ISSN"}]},"item_12_source_id_23":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11561468","subitem_source_identifier_type":"NCID"}]},"item_12_text_10":{"attribute_name":"Author ID","attribute_value_mlt":[{"subitem_text_value":"000242"},{"subitem_text_value":"-"},{"subitem_text_value":"000064"},{"subitem_text_value":"000416"},{"subitem_text_value":"000277"}]},"item_12_text_11":{"attribute_name":"所属機関","attribute_value_mlt":[{"subitem_text_value":"麻布大学生物科学総合研究所"},{"subitem_text_value":"麻布大学生物科学総合研究所"},{"subitem_text_value":"麻布大学獣医学部附属動物病院"},{"subitem_text_value":"麻布大学獣医学部内科学第三研究室"},{"subitem_text_value":"麻布大学獣医学部内科学第三研究室"}]},"item_12_text_12":{"attribute_name":"Institution or Company","attribute_value_mlt":[{"subitem_text_value":"Research Institute of Biosciences, Azabu University, School of Veterinary Medicine"},{"subitem_text_value":"Research Institute of Biosciences, Azabu University, School of Veterinary Medicine"},{"subitem_text_value":"Animal Teaching Hospital, Azabu University, School of Veterinary Medicine"},{"subitem_text_value":"Laboratory of Internal Medicine 3, Azabu University, School of Veterinary Medicine"},{"subitem_text_value":"Laboratory of Internal Medicine 3, Azabu University, School of Veterinary Medicine"}]},"item_12_text_9":{"attribute_name":"著者ID","attribute_value_mlt":[{"subitem_text_value":"000242"},{"subitem_text_value":"-"},{"subitem_text_value":"000064"},{"subitem_text_value":"000416"},{"subitem_text_value":"000277"}]},"item_12_version_type_29":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_12_version_type_30":{"attribute_name":"text 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Reiichiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Onda, Ken","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2015-04-18"}],"displaytype":"detail","filename":"bull_jau_vol26-011.pdf","filesize":[{"value":"553.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"bull_jau_vol26-011.pdf","url":"https://az.repo.nii.ac.jp/record/4111/files/bull_jau_vol26-011.pdf"},"version_id":"3323b0fb-5c53-4d6d-bd51-a45d833ae5f8"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"イヌのグルコース輸送体4（GluT4）の分子構造と組織発現","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"イヌのグルコース輸送体4（GluT4）の分子構造と組織発現"},{"subitem_title":"Molecular structure and distribution of canine glucose transporter 4 (GluT4)","subitem_title_language":"en"}]},"item_type_id":"12","owner":"4","path":["480"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-20"},"publish_date":"2015-03-20","publish_status":"0","recid":"4111","relation_version_is_last":true,"title":["イヌのグルコース輸送体4（GluT4）の分子構造と組織発現"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2023-06-19T08:06:52.392622+00:00"}