{"created":"2023-06-19T07:18:32.492280+00:00","id":3929,"links":{},"metadata":{"_buckets":{"deposit":"8be2baba-f9c6-44e4-83d2-cd820ecb3bc9"},"_deposit":{"created_by":4,"id":"3929","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"3929"},"status":"published"},"_oai":{"id":"oai:az.repo.nii.ac.jp:00003929","sets":["17:36:215","31:181:468"]},"author_link":["18063","18062"],"item_12_biblio_info_16":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"238","bibliographicPageStart":"237","bibliographicVolumeNumber":"17/18","bibliographic_titles":[{"bibliographic_title":"麻布大学雑誌"},{"bibliographic_title":"Journal of Azabu University","bibliographic_titleLang":"en"}]}]},"item_12_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ショウジョウバエ卵巣は，多細胞生物の器官構築過程を研究する良いモデルとなっている。我々が単離した卵巣形態異常の突然変異体のうち，主にchickadee変異体について間接蛍光抗体法と共焦点レーザー顕微鏡で解析した。変異体３令幼虫卵巣では，始原生殖細胞数の減少，２核化が観察された。変異部位は第１イントロン内であった。chickadeeは，収縮環による細胞質分裂の制御を通じて，幼虫期の生殖系列細胞の増殖や分化に関与していると考えられる。","subitem_description_type":"Abstract"}]},"item_12_description_14":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Drosophila ovary serves as a genetically tractable model for the study of stem cell biology, pattern formation, cell migration and cell proliferation. Regulation of cell division is a crucial aspect in the development of multicellular organisms. The embryonic gonad in Drosophila carries about 12 primordial germ cells (PGCs). PGCs proliferate in the female gonad during the subsequent three larval stages until, at the late-third larval stage, the gonad carries over 100 germ cells. Here we show that profilin gene is required for proper mitotic division of PGCs during larval growth. Profilin mutant contains a reduced number of PGCs that are occasionally binucleated. Inverse PCR revealed that the insertion site of our P-element insertion allele is within the intron 1. Three ligands for profilin have been well-characterized in vitro: actin monomers, membrane polyphosphoinositides and poly-L-proline. Profilin may be involved in the formation of cleavage furrows, resulting in proper cytokinesis of PGCs in Drosophila larval ovary","subitem_description_type":"Other"}]},"item_12_description_2":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_12_description_3":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_description":"特集","subitem_description_type":"Other"}]},"item_12_description_34":{"attribute_name":"format","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_12_description_4":{"attribute_name":"Type","attribute_value_mlt":[{"subitem_description":"FEATURE ARTICLES","subitem_description_type":"Other"}]},"item_12_publisher_19":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"麻布大学"}]},"item_12_publisher_20":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Azabu University"}]},"item_12_source_id_21":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-5880","subitem_source_identifier_type":"ISSN"}]},"item_12_source_id_23":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11561468","subitem_source_identifier_type":"NCID"}]},"item_12_text_10":{"attribute_name":"Author ID","attribute_value_mlt":[{"subitem_text_value":"000235"}]},"item_12_text_11":{"attribute_name":"所属機関","attribute_value_mlt":[{"subitem_text_value":"麻布大学"}]},"item_12_text_12":{"attribute_name":"Institution or Company","attribute_value_mlt":[{"subitem_text_value":"Azabu University"}]},"item_12_text_9":{"attribute_name":"著者ID","attribute_value_mlt":[{"subitem_text_value":"000235"}]},"item_12_version_type_29":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_12_version_type_30":{"attribute_name":"text version","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"秋山, 孝洋"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Akiyama, Takahiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-04-17"}],"displaytype":"detail","filename":"bull_jau_vol17-18-237.pdf","filesize":[{"value":"110.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"bull_jau_vol17-18-237","url":"https://az.repo.nii.ac.jp/record/3929/files/bull_jau_vol17-18-237.pdf"},"version_id":"5869dc4b-de8e-43fa-b158-1587d44a625e"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ショウジョウバエ卵巣形成の発生学的解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ショウジョウバエ卵巣形成の発生学的解析"},{"subitem_title":"Developmental analysis of the ovary morphogenesis in Drosophila melanogaster","subitem_title_language":"en"}]},"item_type_id":"12","owner":"4","path":["215","468"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-02-21"},"publish_date":"2014-02-21","publish_status":"0","recid":"3929","relation_version_is_last":true,"title":["ショウジョウバエ卵巣形成の発生学的解析"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2023-06-19T08:22:58.156024+00:00"}