{"created":"2023-06-19T07:18:32.163005+00:00","id":3922,"links":{},"metadata":{"_buckets":{"deposit":"34cc4b13-52c9-44a3-830f-9a76874ac26b"},"_deposit":{"created_by":4,"id":"3922","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"3922"},"status":"published"},"_oai":{"id":"oai:az.repo.nii.ac.jp:00003922","sets":["17:234:212","17:234:238","17:257:355","17:38:273","31:181:468"]},"author_link":["18036","18039","18043","18034","18041","18035","18037","18042","18040","18038"],"item_12_biblio_info_16":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"210","bibliographicPageStart":"202","bibliographicVolumeNumber":"17/18","bibliographic_titles":[{"bibliographic_title":"麻布大学雑誌"},{"bibliographic_title":"Journal of Azabu University","bibliographic_titleLang":"en"}]}]},"item_12_description_14":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Resistance to intestinal proteases and efficacy against verotoxin (VT) 2 of a colostral antibody administered orally via catheter were investigated in beagle dogs. Bovine colostral antibody remained in the small intestine for 2 hours, whereas little serum antibody remained at 1.5 hours after administration. The bovine colostral antibody was not inactivated by proteases in the small intestine. Furthermore, the antibody activity of S-IgA did not change until 2 hours after administration; however, the activity of IgG and IgM antibodies decreased by two-thirds and two-fifths at 2 hours after administration, respectively.\n Seven beagle dogs inoculated with Escherichia coli (E. coli) O157:H7 producing VT2 were administered bovine colostral antibody or bovine colostral whey without antibody. With administration of bovine colostral whey without antibody, the amount of VT2 in feces decreased gradually after administration and increased again at 5 days after inoculation, while bovine colostral antibody significantly reduced the amount of VT2 in feces the day after administration. In addition, 9 beagle dogs were administered bovine colostral antibody, bovine plasma antibody or saline. The amount of VT2 in feces also significantly reduced rapidly after administration of bovine colostral antibody than administration of bovine plasma antibody or saline.","subitem_description_type":"Other"}]},"item_12_description_2":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_12_description_3":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_description":"特集","subitem_description_type":"Other"}]},"item_12_description_34":{"attribute_name":"format","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_12_description_4":{"attribute_name":"Type","attribute_value_mlt":[{"subitem_description":"FEATURE ARTICLES","subitem_description_type":"Other"}]},"item_12_publisher_19":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"麻布大学"}]},"item_12_publisher_20":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Azabu University"}]},"item_12_source_id_21":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-5880","subitem_source_identifier_type":"ISSN"}]},"item_12_source_id_23":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11561468","subitem_source_identifier_type":"NCID"}]},"item_12_text_10":{"attribute_name":"Author ID","attribute_value_mlt":[{"subitem_text_value":"000117"},{"subitem_text_value":"000345"},{"subitem_text_value":"-"},{"subitem_text_value":"000119"},{"subitem_text_value":"000279"}]},"item_12_text_11":{"attribute_name":"所属機関","attribute_value_mlt":[{"subitem_text_value":"麻布大学生命・環境科学部免疫学研究室"},{"subitem_text_value":"麻布大学生命・環境科学部免疫学研究室"},{"subitem_text_value":"麻布大学生命・環境科学部免疫学研究室"},{"subitem_text_value":"麻布大学生命・環境科学部微生物学研究室"},{"subitem_text_value":"麻布大学生命・環境科学部微生物学研究室"}]},"item_12_text_12":{"attribute_name":"Institution or Company","attribute_value_mlt":[{"subitem_text_value":"Laboratories of Immunology, School of Life and Environmental Science, Azabu University"},{"subitem_text_value":"Laboratories of Immunology, School of Life and Environmental Science, Azabu University"},{"subitem_text_value":"Laboratories of Immunology, School of Life and Environmental Science, Azabu University"},{"subitem_text_value":"Laboratories of Microbiology, School of Life and Environmental Science, Azabu University"},{"subitem_text_value":"Laboratories of Microbiology, School of Life and Environmental Science, Azabu University"}]},"item_12_text_9":{"attribute_name":"著者ID","attribute_value_mlt":[{"subitem_text_value":"000117"},{"subitem_text_value":"000345"},{"subitem_text_value":"-"},{"subitem_text_value":"000119"},{"subitem_text_value":"000279"}]},"item_12_version_type_29":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_12_version_type_30":{"attribute_name":"text version","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山本, 静雄"}],"nameIdentifiers":[{"nameIdentifier":"18034","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"栗林, 尚志"}],"nameIdentifiers":[{"nameIdentifier":"18035","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"清田, 哲郎"}],"nameIdentifiers":[{"nameIdentifier":"18036","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福山, 正文"}],"nameIdentifiers":[{"nameIdentifier":"18037","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古畑, 勝則"}],"nameIdentifiers":[{"nameIdentifier":"18038","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamoto, Shizuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18039","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kuribayashi, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18040","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Seita, Tetsuro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18041","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Furuhata, Katsunori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18042","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukuyama, Masafumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"18043","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-04-17"}],"displaytype":"detail","filename":"bull_jau_vol17-18-202.pdf","filesize":[{"value":"669.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"bull_jau_vol17-18-202","url":"https://az.repo.nii.ac.jp/record/3922/files/bull_jau_vol17-18-202.pdf"},"version_id":"5ac44ee5-fadb-4cf3-8c78-81b5256283d9"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"初乳抗体の腸管内での作用に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"初乳抗体の腸管内での作用に関する研究"},{"subitem_title":"Bovine immune colostral antibody against verotoxin 2 derived from Escherichia coli O157:H7-resistance to proteases and effects on verotoxin 2 in small intestine of beagle dogs","subitem_title_language":"en"}]},"item_type_id":"12","owner":"4","path":["212","238","273","355","468"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-02-21"},"publish_date":"2014-02-21","publish_status":"0","recid":"3922","relation_version_is_last":true,"title":["初乳抗体の腸管内での作用に関する研究"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2023-06-19T08:23:05.331883+00:00"}