{"created":"2023-06-19T07:18:23.616324+00:00","id":3737,"links":{},"metadata":{"_buckets":{"deposit":"d2432c04-2444-4f10-8136-0d0b71a41baa"},"_deposit":{"created_by":4,"id":"3737","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"3737"},"status":"published"},"_oai":{"id":"oai:az.repo.nii.ac.jp:00003737","sets":["17:236:230","17:254:344","17:257:357","31:181:453"]},"author_link":["17491","17493","17495","17497","17499","17498","17494","17492","17496"],"item_12_biblio_info_16":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-01-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"35","bibliographicPageStart":"31","bibliographicVolumeNumber":"24","bibliographic_titles":[{"bibliographic_title":"麻布大学雑誌"},{"bibliographic_title":"Journal of Azabu University","bibliographic_titleLang":"en"}]}]},"item_12_description_14":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Purpose: We investigated the association between paraoxonase 1 (PON1)-192 genotypes and intimamedia thickness (IMT) of carotid arteries in diabetic patients.\n Methods: One hundred and fifty-five Japanese type 2 diabetic patients aged from 40 to 79 years were enrolled in this study. Genotypes of the patients were determined using the PCR-RFLP method. The IMT of carotid arteries of the subjects was measured by ultrasound imaging.\n Results: The PON1 genotypes frequencies were as follows: 18QQ (0.116), 70QR (0.452) and 67RR (0.432). IMT values of the RR group were significantly greater (1.08±0.41 mm, n=67) than those of the Q group, which consisted of patients carrying one or two Q alleles (0.95±0.27 mm, n=88, P=0.023). There were no significant difference in the clinical characteristics between the two groups.\n Conclusion: The results indicate that the PON1-192RR genotype is associated with intima media thickening of the carotid arteries in diabetic patients.\n","subitem_description_type":"Other"}]},"item_12_description_2":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_12_description_24":{"attribute_name":"NII論文ID(NAID)","attribute_value_mlt":[{"subitem_description":"40019736749","subitem_description_type":"Other"}]},"item_12_description_3":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_description":"原著論文","subitem_description_type":"Other"}]},"item_12_description_34":{"attribute_name":"format","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_12_description_4":{"attribute_name":"Type","attribute_value_mlt":[{"subitem_description":"ORIGINAL ARTICLE","subitem_description_type":"Other"}]},"item_12_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.14944/00003716","subitem_identifier_reg_type":"JaLC"}]},"item_12_publisher_19":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"麻布大学"}]},"item_12_publisher_20":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Azabu University"}]},"item_12_source_id_21":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-5880","subitem_source_identifier_type":"ISSN"}]},"item_12_source_id_23":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11561468","subitem_source_identifier_type":"NCID"}]},"item_12_text_10":{"attribute_name":"Author ID","attribute_value_mlt":[{"subitem_text_value":"000383"},{"subitem_text_value":"000386"},{"subitem_text_value":"-"},{"subitem_text_value":"-"},{"subitem_text_value":"-"},{"subitem_text_value":"-"},{"subitem_text_value":"-"},{"subitem_text_value":"-"},{"subitem_text_value":"000380"}]},"item_12_text_12":{"attribute_name":"Institution or Company","attribute_value_mlt":[{"subitem_text_value":"School of Life and Environmental Science, Azabu University"},{"subitem_text_value":"School of Life and Environmental Science, Azabu University"},{"subitem_text_value":"Faculty of Pharmacy, Hyogo University of Health Sciences"},{"subitem_text_value":"Faculty of Pharmacy, Hyogo University of Health Sciences"},{"subitem_text_value":"Department of Internal Medicine, NTT West Osaka Hospital"},{"subitem_text_value":"Department of Internal Medicine, NTT West Osaka Hospital"},{"subitem_text_value":"Clinical Evaluation of Medicines and Therapeutics, Graduate School of Pharmaceutical Scienes, Osaka University"},{"subitem_text_value":"Faculty of Pharmacy, Hyogo University of Health Sciences"},{"subitem_text_value":"School of Life and Environmental Science, Azabu University"}]},"item_12_version_type_29":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_12_version_type_30":{"attribute_name":"text version","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Honda, Teruko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takada, Kayoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Makiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nonen, Sinpei","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Motomura, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Keiji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujio, Yasushi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Azuma, Junichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Isamu \\n","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-03-27"}],"displaytype":"detail","filename":"bull_jau_vol24-031.pdf","filesize":[{"value":"476.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"bull_jau_vol24-031","url":"https://az.repo.nii.ac.jp/record/3737/files/bull_jau_vol24-031.pdf"},"version_id":"5e3da37c-d6f3-45a6-a660-8172d637f169"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"paraoxonase 1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"genetic polymorphism","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"intima-media thickness (IMT)","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Association of paraoxonase 1 gene polymorphism with Intima-Media Thickness (IMT) of the carotid arteries in japanese type 2 diabetic patients","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Association of paraoxonase 1 gene polymorphism with Intima-Media Thickness (IMT) of the carotid arteries in japanese type 2 diabetic patients","subitem_title_language":"en"}]},"item_type_id":"12","owner":"4","path":["230","344","357","453"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-03-20"},"publish_date":"2014-03-20","publish_status":"0","recid":"3737","relation_version_is_last":true,"title":["Association of paraoxonase 1 gene polymorphism with Intima-Media Thickness (IMT) of the carotid arteries in japanese type 2 diabetic patients"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2023-12-19T05:59:34.847941+00:00"}