{"created":"2023-06-19T07:18:20.965346+00:00","id":3679,"links":{},"metadata":{"_buckets":{"deposit":"91b40e7d-d2c9-45af-9662-33a4d0fced4a"},"_deposit":{"created_by":4,"id":"3679","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"3679"},"status":"published"},"_oai":{"id":"oai:az.repo.nii.ac.jp:00003679","sets":["17:253:318","17:36:213","17:37:219","31:181:451"]},"author_link":["17375","17379","17378","17380","17381","17376","17377","17374"],"item_12_biblio_info_16":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-03-31","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"134","bibliographicPageStart":"129","bibliographicVolumeNumber":"21/22","bibliographic_titles":[{"bibliographic_title":"麻布大学雑誌"},{"bibliographic_title":"Journal of Azabu University","bibliographic_titleLang":"en"}]}]},"item_12_description_13":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"先天性過骨症は，前肢の硬化・腫脹を特徴とする新生豚の稀な疾患である。本疾患は常染色体の劣性遺伝によるものと考えられているが，原因や発生機序は明らかにされていない。病変部は四肢に限局し，橈骨・尺骨で顕著である。我々は分娩直後に死亡した雌の子豚に前肢の硬化・腫脹を認め，病理学的に先天性過骨症と診断した。組織学的に腫脹していた橈骨・尺骨では線維性骨梁が皮質骨表面から放射状に伸長し，周囲骨格筋は変性・萎縮し，線維化していた。後肢やその他臓器には著変はみられなかった。鑑別診断として，先天性筋症と肺性肥大性骨症が挙げられるが，前者は本例の病変が骨に主座し筋原線維の一次性構造異常がないことから，また後者は造骨形態や胸腔内に腫瘤病変がないことから否定された。","subitem_description_type":"Abstract"}]},"item_12_description_14":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Congenital hyperostosis is a rare disease of newborn pigs, characterized by thickening and sclerosis of the forelimbs. It has been suspected that it is inherited as an autosomal recessive trait, but the pathogenesis of the bone abnormalities has not been clarified. The lesions are characteristically localized in the limbs, and the radius and ulna are the most severely affected. We examined a female piglet who died right after delivery; the piglet showed thickening and sclerosis of the forelimbs, and the bone lesions were diagnosed as congenital hyperostosis. Histologically, fibrous trabecular bone proliferated radially and extended out from the surface of cortical bone of the swollen radius and ulna. The skeletal muscles around the bones showed degeneration and atrophy with fibrosis. No lesions were found in other bones and organs. For the differential diagnosis, congenital myopathy and pulmonary hypertrophic osteopathy were considered, but myopathy was excluded because of the lesion distribution and the absence of a primary structural abnormality of myofibrils, while pulmonary hypertrophic osteopathy was also excluded because of the different form of osteogenesis and the absence of a tumor in the thoracic cavity.","subitem_description_type":"Other"}]},"item_12_description_2":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_12_description_24":{"attribute_name":"NII論文ID(NAID)","attribute_value_mlt":[{"subitem_description":"40018959135","subitem_description_type":"Other"}]},"item_12_description_3":{"attribute_name":"記事種別","attribute_value_mlt":[{"subitem_description":"特集","subitem_description_type":"Other"}]},"item_12_description_34":{"attribute_name":"format","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_12_description_4":{"attribute_name":"Type","attribute_value_mlt":[{"subitem_description":"FEATURE ARTICLES","subitem_description_type":"Other"}]},"item_12_publisher_19":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"麻布大学"}]},"item_12_publisher_20":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Azabu University"}]},"item_12_source_id_21":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-5880","subitem_source_identifier_type":"ISSN"}]},"item_12_source_id_23":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11561468","subitem_source_identifier_type":"NCID"}]},"item_12_text_10":{"attribute_name":"Author ID","attribute_value_mlt":[{"subitem_text_value":"-"},{"subitem_text_value":"000351"},{"subitem_text_value":"000329"},{"subitem_text_value":"000049"}]},"item_12_text_11":{"attribute_name":"所属機関","attribute_value_mlt":[{"subitem_text_value":"麻布大学生物科学総合研究所"},{"subitem_text_value":"麻布大学獣医学部内科学第一研究室"},{"subitem_text_value":"麻布大学獣医学部内科学第一研究室"},{"subitem_text_value":"麻布大学生物科学総合研究所, 麻布大学生獣医学部病理学研究室"}]},"item_12_text_12":{"attribute_name":"Institution or Company","attribute_value_mlt":[{"subitem_text_value":"Research Institute of Biosciences, Azabu University"},{"subitem_text_value":"Laboratory of Veterinary Internal Medicine I, School of Veterinary Medicine, Azabu University"},{"subitem_text_value":"Laboratory of Veterinary Internal Medicine I, School of Veterinary Medicine, Azabu University"},{"subitem_text_value":"Research Institute of Biosciences and  Laboratory of Veterinary Pathology, Azabu University"}]},"item_12_text_9":{"attribute_name":"著者ID","attribute_value_mlt":[{"subitem_text_value":"-"},{"subitem_text_value":"000351"},{"subitem_text_value":"000329"},{"subitem_text_value":"000049"}]},"item_12_version_type_29":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_12_version_type_30":{"attribute_name":"text version","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"藍澤, 重之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"新井, 佐知子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"伊東, 正吾"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"代田, 欣二"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Aizawa, Shigeyuki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Arai, Sachiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ito, Seigo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shirota, Kinji","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-03-27"}],"displaytype":"detail","filename":"bull_jau_vol21-22-129.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"bull_jau_vol21-22-129","url":"https://az.repo.nii.ac.jp/record/3679/files/bull_jau_vol21-22-129.pdf"},"version_id":"7c69e6b0-01e5-496a-b7fe-f352df789a29"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Bone","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"congenital hyperostosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"newborn pig","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pathology","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"新生豚にみられた先天性過骨症","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"新生豚にみられた先天性過骨症"},{"subitem_title":"Congenital hyperostosis in a newborn pig","subitem_title_language":"en"}]},"item_type_id":"12","owner":"4","path":["213","219","318","451"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-02-25"},"publish_date":"2014-02-25","publish_status":"0","recid":"3679","relation_version_is_last":true,"title":["新生豚にみられた先天性過骨症"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2023-12-19T06:00:24.737557+00:00"}