| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-02-28 |
| タイトル |
|
|
タイトル |
Prelimbic cortex responds to male ultrasonic vocalizations in the presence of a male pheromone in female mice |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Asaba, Akari
Nomoto, Kensaku
Osakada, Takuya
Matsuo, Tomohiko
Kobayakawa, Ko
Kobayakawa, Reiko
Touhara, Kazushige
Mogi, Kazutaka
Kikusui, Takefumi
|
| Abstract |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Sensory signals are critical to perform adaptive social behavior. During copulation, male mice emit ultrasonic vocalizations (USVs). Our previous studies have shown that female mice exhibit approach behavior toward sound sources of male USVs and that, after being exposed to a male pheromone, exocrine gland-secreting peptide 1 (ESP1), female mice exhibited a preference toward a particular type of male USVs. These findings suggest that male USVs modulate female courtship behavior. However, it remains unclear which brain regions and what cell types of neurons are involved in neuronal processing of male USVs. To clarify this issue, immediate early gene analysis, behavioral analysis, and neurochemical analysis were performed. The in situ hybridization analysis of c-fos mRNA in multiple brain regions showed that neurons in the prelimbic cortex were responsive to presentation of male USVs in the presence of ESP1. Furthermore, this study found that activity of prelimbic cortex was correlated with the duration of female exploration behavior toward a sound source of the USVs. Finally, by using double immunohistochemistry, the present study showed that the prelimbic neurons responding to the presentation of male USVs were presumably excitatory glutamatergic neurons. These results suggest that the prelimbic cortex may facilitate female courtship behavior in response to male USVs. |
|
言語 |
en |
| 書誌情報 |
Frontiers in neural circuits
巻 16,
p. 956201-956201,
発行日 2022-09-28
|
| 出版者 |
|
|
出版者 |
Frontiers Media SA |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.3389/fncir.2022.956201 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 査読 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
査読あり |
fncir-16-956201.pdf (4 MB)
