| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-02-28 |
| タイトル |
|
|
タイトル |
A cat with myelodysplastic syndrome by administration of the methylation inhibitor Azacytidine |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Hisasue, Masaharu
Tanaka, Mina
Neo, Sakurako
|
| Abstract |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
A 5-year-old female cat with nonregenerative anemia and thrombocytopenia was diagnosed with myelodysplastic syndromes (MDS), since peripheral blood and bone marrow (BM) examination revealed various dysplasias and a blast ratio of 19%. Chemotherapy with azacytidine (AZA; 70-35 mg/m2, 3-5 days, three cycles) and treatment with prednisolone, antibiotics, and vitamin K2, and blood transfusion were performed. On day 106, blast cells and dysplasia had decreased in the BM, and the cat remained alive for at least 1,474 days. This report is the first on feline MDS treated with AZA, suggesting appropriate drug dosage, interval and effective combination should be investigated and the pharmacological and cell biological mechanisms needs to be elucidated in the future. |
|
言語 |
en |
| 書誌情報 |
The Journal of Veterinary Medical Science
巻 84,
号 1,
p. 142-148,
発行日 2022-01-24
|
| 出版者 |
|
|
出版者 |
The Japanese Society of Veterinary Science |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0916-7250 |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1292/jvms.20-0352 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 査読 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
査読あり |
84_20-0352.pdf (1.4 MB)
