| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-02-14 |
| タイトル |
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|
タイトル |
Effect of glycyrrhizin administration followed by symptom-based antimicrobial selection therapy on antimicrobial use in clinical mastitis without systemic symptoms |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Kurumisawa, Tomomi
Yagisawa, Takuya
Shinozuka, Yasunori
Kawai, Kazuhiro
|
| Abstract |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
In bovine mastitis, antimicrobial treatment is often initiated before the causative organism is identified a problem in the prudent use of antimicrobials. In this study, we aimed to reduce the total amount of antimicrobials used in mastitis treatment by administering glycyrrhizin, an anti-inflammatory drug, instead of antimicrobials at the onset of clinical mastitis without systemic symptoms, followed by symptom-based antimicrobial selection therapy (ST), to examine the effect of this treatment strategy on treatment outcomes and antimicrobial use. Comparisons between cases that received antimicrobial treatment starting from the day of diagnosis (blanket antibiotic therapy [BT] group: 33 cases) and cases that received ST starting from the day after the diagnosis (ST group: 57 cases) revealed no difference in the cure rate, milk withholding period, or recurrence rate. However, the ST group had a significantly lower amount of antimicrobials than the BT group. Additionally, a single administration of glycyrrhizin before ST significantly relieved the udder symptoms and reduced the antimicrobial amount when compared with cases without glycyrrhizin administration. Thus, a single administration of glycyrrhizin followed by ST can reduce the total antimicrobial use. |
|
言語 |
en |
| 書誌情報 |
The Journal of Veterinary Medical Science
巻 84,
号 9,
p. 1265-1271,
発行日 2022-09-12
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| 出版者 |
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|
出版者 |
The Japanese Society of Veterinary Science |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0916-7250 |
| DOI |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.1292/JVMS.22-0108 |
| 著者版フラグ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 査読 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
査読あり |
84_22-0108.pdf (1 MB)
