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Predicting an increased risk of severe clinical mastitis and economic loss using a threshold value of bovine leukemia virus proviral load
https://az.repo.nii.ac.jp/records/2000253
https://az.repo.nii.ac.jp/records/20002539b9d0c52-8c6b-44b9-bfca-e13182e09244
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||||
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公開日 | 2025-01-15 | |||||||||||||||||||||||
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タイトル | Predicting an increased risk of severe clinical mastitis and economic loss using a threshold value of bovine leukemia virus proviral load | |||||||||||||||||||||||
言語 | en | |||||||||||||||||||||||
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言語 | eng | |||||||||||||||||||||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||||
資源タイプ | journal article | |||||||||||||||||||||||
著者 |
Watanabe, Aiko
× Watanabe, Aiko
× Murakami, Hironobu
× Kakinuma, Seiichi
× Murao, Koki
× Oomae, Kaori
× Akamatsu, Hirohisa
× Seto, Takahiro
× Shinozuka, Yasunori
× Kawai, Kazuhiro
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Abstract | ||||||||||||||||||||||||
内容記述タイプ | Abstract | |||||||||||||||||||||||
内容記述 | OBJECTIVE To establish a threshold value of bovine leukemia virus (BLV) proviral load (PVL) to identify increased risk of severe clinical mastitis, and to examine the prognosis and economic loss of clinical mastitis based on the newly established PVL cut-off value. ANIMALS 97 lactating Holstein cows with clinical mastitis. METHODS Blood and milk samples were collected aseptically from each cow. Youden index was used for receiver-operating characteristic curve analysis with the severity rate of clinical mastitis as the dependent variable and PVL as an independent variable. PVL cut-off value was used as a criterion to compare the severity rate of clinical mastitis, percentage of cows with and without systemic treatments, number of treatments, cost of treatment, and prognosis. RESULTS PVL cut-off value was 17.8 copies/10 ng DNA for the dependent variable MILD vs SEVERE. The severity rate of clinical mastitis, percentage of cows given systemic treatments, and technical fees for medical treatment were significantly higher in the group above the PVL cut-off value than in the group below the PVL cut-off value and the negative group. Number of treatments was significantly higher in the group above the cut-off value than in the group below the cut-off value. There was no significant difference in prognosis after mastitis among the 3 groups. CLINICAL RELEVANCE These results suggested that PVL cut-off value of 17.8 copies/10 ng DNA was a useful threshold for increased economic losses in BLV-infected cows; it may also serve as a new standard value for the detection and culling of BLV-infected cows in Japan. |
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言語 | en | |||||||||||||||||||||||
書誌情報 |
American Journal of Veterinary Research 巻 85, 号 3, p. 1-9, 発行日 2023-12-27 |
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出版者 | American Veterinary Medical Association (AVMA) | |||||||||||||||||||||||
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収録物識別子タイプ | ISSN | |||||||||||||||||||||||
収録物識別子 | 0002-9645 | |||||||||||||||||||||||
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識別子タイプ | DOI | |||||||||||||||||||||||
関連識別子 | 10.2460/ajvr.23.09.0198 | |||||||||||||||||||||||
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出版タイプ | VoR | |||||||||||||||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||||
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内容記述タイプ | Other | |||||||||||||||||||||||
内容記述 | 査読あり |