| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-12-24 |
| タイトル |
|
|
タイトル |
Omega-3 fatty acids mitigate skin damage caused by ultraviolet-B radiation |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Harauma, Akiko
Enomoto, Yui
Endo, Sayaka
Hariya, Himeka
Moriguchi, Toru
|
| Abstract |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Mice fed a diet containing an adequate amount of ω-3 fatty acids (ω-3 Adq) or a deficient diet (ω-3 Def) were irradiated with ultraviolet-B (UV-B) and were measured daily changes in transepidermal water loss (TEWL). TEWL was significantly increased in ω-3 Def mice with repeated UV-B irradiation, but this increase was significantly reduced in ω-3 Adq mice. The epidermal layers revealed thickening of the spinous and basal layers induced by UV-B irradiation in both groups. Moreover, the ω-3 Def mice had a disturbed epidermal structure and a coarser stratum corneum. And the granule cell layer is significantly reduced, and abnormal layer formation (parakeratosis) occurred in the stratum corneum. These results suggest that continuous UV-B irradiation promotes epidermal turnover and leads to epidermal thickening, but ω-3 fatty acids protect the body from UV-B-induced stress. |
|
言語 |
en |
| 書誌情報 |
Prostaglandins, Leukotrienes, and Essential Fatty Acids
巻 203,
p. 102641-102641,
発行日 2024-09-11
|
| 出版者 |
|
|
出版者 |
Elsevier |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1016/j.plefa.2024.102641 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 査読 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
査読あり |
1-s2.0-S0952327824000358-main.pdf (3.6 MB)
