2026-03-07T15:20:01Z https://az.repo.nii.ac.jp/oai

oai:az.repo.nii.ac.jp:00004455 2023-06-19T07:48:47Z 17:253:315 31:181:487

形質転換植物を用いたダイオキシン類による汚染環境のバイオモニタリングに関する基礎研究 Studies on biomonitoring and phytoremediation of dioxins in the polluted environment using transgenie plants. 其木, 成則 Sonoki, Shigenori マイクロアレイ法を用いて,シロイヌナズナの約1万のcDNAの中からPCB126暴露によって発現が促進される可能性のある遺伝子が4つ見いだされた。 The stability and hydrophobic nature of polychlorinated biphenyls (PCBs) make them a persistent environmental hazard; thus, the environmental pollution level of PCBs has been kept high for a long time especially in Japan. Among many PCB congeners, the high environmental toxicity of coplanar PCBs (Co-PCBs) is becoming more severe. In this study, the gene (s) that, respond to the chemical stress of Co-PCBs in the genome of plant, Arabidopsis thaliana, was (were) searched using cDNA microarray. This study, which intends to use the plant gene (s) as a biomarker for monitoring the environmental levels of Co-PCBs, is expected to lead to the development of a new strategy in the risk assessment of Co-PCBs contamination. As a result, four cDNAs were found, which look like the up-regulated genes responding to PCB 126 exposure for 48hours, in about 9,000 cDNA fragments. These genes are expected to be the candidate for a biomarker in the environmental monitoring of Co-PCBs. 麻布大学ハイテク・リサーチ・センター研究プロジェクト 研究サブ・グループ3 P(論文) 特集 application/pdf FEATURE ARTICLES departmental bulletin paper 麻布大学 Azabu University 2003-03-31 VoR VoR application/pdf 麻布大学雑誌 5/6 209 210 Journal of Azabu University 1346-5880 AA11561468 https://az.repo.nii.ac.jp/record/4455/files/bull_jau_vol5-6-209.pdf https://az.repo.nii.ac.jp/records/4455 jpn