2026-03-09T15:34:06Z https://az.repo.nii.ac.jp/oai

oai:az.repo.nii.ac.jp:02000359 2025-02-26T07:58:11Z 423

Case Report: Detection of Transferrin in a Dog Suspected of Having Cerebrospinal Fluid Rhinorrhea Kinoshita, Kosuke Kinoshita Kosuke Nishida, Hidetaka Nishida Hidetaka Kanegi, Ryoji Kanegi Ryoji Nakamoto, Yuya Nakamoto Yuya Tanaka, Toshiyuki Tanaka Toshiyuki Shimamura, Shunsuke Shimamura Shunsuke Kusumoto, Kazuhito Kusumoto Kazuhito Akiyoshi, Hideo Akiyoshi Hideo A 12-year-old Yorkshire terrier was referred for epileptic seizures and nasal discharge. The fluid was clear and serous. Cerebrospinal fluid (CSF) rhinorrhea was suspected, based on clinical signs and MRI findings. In humans, analysis of nasal secretions to determine the concentration of glucose and brain-type transferrin has been widely used clinically in order to confirm the presence of CSF rhinorrhea. The glucose concentration in the nasal discharge was 74 mg/dL. Serum-type and brain-type isoforms of transferrin were detectable in the nasal sample. The concentration of glucose and brain-type transferrin could be useful for diagnosing CSF rhinorrhea. Frontiers Media SA 2022-03-04 eng journal article VoR https://az.repo.nii.ac.jp/records/2000359 10.3389/fvets.2022.845809 Frontiers in Veterinary Science 9 845809 845809 https://az.repo.nii.ac.jp/record/2000359/files/fvets-09-845809.pdf application/pdf 462 KB 2025-02-28