WEKO3
アイテム
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有用細菌(乳酸菌等)の全ゲノム塩基配列決定,比較ゲノム解析および有用遺伝子の機能解明 : 第3報
https://az.repo.nii.ac.jp/records/4874
https://az.repo.nii.ac.jp/records/4874167b2746-8e69-4729-918f-4d2cccff8836
名前 / ファイル | ライセンス | アクション |
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bull_jau_vol11-12-247.pdf (386.1 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2005-01-01 | |||||
タイトル | ||||||
タイトル | 有用細菌(乳酸菌等)の全ゲノム塩基配列決定,比較ゲノム解析および有用遺伝子の機能解明 : 第3報 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Complete sequence, comparative genomics and post-genome analysis of lactic acid bacteria | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
ページ属性 | ||||||
内容記述タイプ | Other | |||||
内容記述 | P(論文) | |||||
記事種別 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 特集 | |||||
Type | ||||||
内容記述タイプ | Other | |||||
内容記述 | FEATURE ARTICLES | |||||
著者 |
森田, 英利
× 森田, 英利× 堀川, 洋× 鈴木, 武人× 政岡, 俊夫× 福岡, 秀雄× 茅根, 士郎× 和田, 恭則× 有嶋, 和義× 木内, 明男× 坂田, 亮一× 紫野, 正雄× 内藤, 博之× 斉藤, 康秀× 西田, 利穂× 印牧, 信行× 滝沢, 達也× 加藤, 行男× 村上, 賢× 福山, 正文× 岸川, 正剛× 久松, 伸× 吉村, 哲彦× 藤, 英博× 大島, 健志朗× 芝, 忠義× 服部, 正平× Morita, Hidetoshi× Horikawa, Hiroshi× Suzuki, Takahito× Masaoka, Toshio× Fukuoka, Hideo× Chinone, Shiro× Wada, Yasunori× Arishima, Kazuyoshi× Kiuchi, Akio× Sakata, Ryoichi× Shino, Masao× Naito, Hiroyuki× Saito, Yasuhide× Nishita, Toshiho× Kanemaki, Nobuyuki× Takizawa, Tatsuya× Kato, Yukio× Murakami, Masaru× Fukuyama, Masafumi× Kishikawa, Seigo× Hisamatsu, Shin× Yoshimura, Tetsuhiko× Toh, Hidehiro× Oshima, Kenshiro× Shiba, Tadayoshi× Hattori, Masahira |
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学獣医学部 | ||||||
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麻布大学健康環境科学部 | ||||||
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麻布大学健康環境科学部 | ||||||
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麻布大学健康環境科学部 | ||||||
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(財)山形県企業振興公社生物ラジカル研究所 | ||||||
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北里大学理学部 | ||||||
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北里大学理学部 | ||||||
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北里大学理学部 | ||||||
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北里大学北里生命科学研究所:理研ゲノム科学総合研究センター | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
Institution or Company | ||||||
School of Veterinary Medicine, Azabu University | ||||||
Institution or Company | ||||||
School of Veterinary Medicine, Azabu University | ||||||
Institution or Company | ||||||
School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Veterinary Medicine, Azabu University | ||||||
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School of Environmental Health Sciences, Azabu University | ||||||
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School of Environmental Health Sciences, Azabu University | ||||||
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School of Environmental Health Sciences, Azabu University | ||||||
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Institute for Life Support Technology, Yamagata Public Corporation for the Development of Industry | ||||||
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School of Science, Kitasato University, Institute of Life Support Technology | ||||||
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School of Science, Kitasato University, Institute of Life Support Technology | ||||||
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School of Science, Kitasato University, Institute of Life Support Technology | ||||||
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Laboratory of Genomic Information, Kitasato Institue for Life Science, Kitasato University : Human genome research group, Genomic Sciences Center, RIKEN Yokohama Institute | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | プロバイオティクス乳酸菌としてLactobacillus reunteri (2, 039, 414 bp),そしてその知見のほとんどみられないLactobacillus fermentum(2, 098, 685 bp)の全ゲノム配列を決定した。両菌種は絶対ヘテロ発酵型の乳酸菌としては初めての全ゲノム配列決定となった。Lactobacillus属には,他にホモ発酵型と条件的ヘテロ発酵型の乳酸菌があるが,上記両菌種では,解糖(EMP)経路では必須の6-phosphofructokinase遺伝子の欠損が明らかとなり,そのためペントース・リン酸経路しか機能しなかった。各ORF内で3つ目の塩基の置換が非常に多く,そのことが遺伝子の機能は変わらず,G+C含量に10%もの違いが生じることが認められた。L. reuteriのゲノム中で多くのmobile elementsを発見したが,それはLactobacillus属が環境への適合性を高くし,生存性を有利にするのに貢献していることが示唆された。 | |||||
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内容記述タイプ | Other | |||||
内容記述 | We present the complete genome sequences of two lactic acid bacteria (LAB), probiotic Lactobacillus reuteri (2, 039, 414 bp) and non-probiotic Lactobacillus fermentum (2, 098, 685 bp), which share obligately the heterofermentative property in glucose metabolism and have a phylogenetically closest relation. The two genomes are compared with each other and with other lactobacilli exhibiting facultatively heterofermentative and obligately homofermentative properties. A striking common feature of the two lactobacilli is a lack of a gene encoding 6-phosphofructokinase essential for the Embden-Meyerhof-Pamas (EMP) pathway, so that the pentose phosphate pathway is utilized in them. Furthermore, numerous mobile elements in L. reuteri is found in the genomes. These data imply that a genetic plasticity-environment relationship may account for the diversity between these lactobacilli. | |||||
書誌情報 |
麻布大学雑誌 en : Journal of Azabu University 巻 11/12, p. 247-251, 発行日 2006-03-31 |
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出版者 | 麻布大学 | |||||
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出版者 | Azabu University | |||||
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収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1346-5880 | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11561468 | |||||
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出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
text version | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
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内容記述タイプ | Other | |||||
内容記述 | application/pdf |